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Dec. 2 US: Notice of Intent to List Intent to List Kresoxim-Methyl and Tetraconazole


The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list the chemicals kresoxim-methyl and tetraconazole as known to the State to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986. This action is being proposed under the authoritative bodies listing mechanism.

(CAS No.)
Endpoint Reference Occurrence
Cancer U.S. EPA (1999) Fungicide used on apples, cherries, grapes, pears, pome fruits and pecans
Cancer U.S. EPA (2000) Triazole fungicide used to control leafspot and powdery mildew on sugar beets

OEHHA requested information relevant to the possible listing of kresoxim-methyl and tetraconazole in a notice published in the California Regulatory Notice Register on October 22, 2010 (Register 2010, Vol. No. 43-Z). OEHHA received public comments on both chemicals.

Background on listing via the authoritative bodies mechanism: A chemical must be listed under the Proposition 65 regulations when two conditions are met:

  1. An authoritative body formally identifies the chemical as causing cancer (Section 25306(d) ).
  2. The evidence considered by the authoritative body meets the sufficiency criteria contained in the regulations (Section 25306(e)).

However, the chemical is not listed if scientifically valid data which were not considered by the authoritative body clearly establish that the sufficiency of evidence criteria were not met (Section 25306(f)).

The U.S. Environmental Protection Agency (U.S. EPA) is one of several institutions designated as authoritative for the identification of chemicals as causing cancer (Section 25306(m)).

OEHHA is the lead agency for Proposition 65 implementation. After an authoritative body has made a determination about a chemical, OEHHA evaluates whether listing under Proposition 65 is required using the criteria contained in the regulations.

OEHHA’s determination: Kresoxim-methyl and tetraconazole each meet the criteria for listing as known to the State to cause cancer under Proposition 65, based on findings of the U.S. EPA (U.S. EPA, 1999; U.S. EPA, 2000).

The full article can be found here.

We will keep you informed of any future updates.

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