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Diaminotoluene (mixed): Request for relevant information on the carcinogenic hazards of diaminotoluenes

This news update on Diaminotoluene (mixed) is brought to you by OEHHA.



The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the implementation of Proposition 651. The Carcinogen Identification Committee (CIC) of OEHHA’s Science Advisory Board serves as the state’s qualified experts and renders an opinion about whether a chemical has been clearly shown to cause cancer. The chemicals identified by the CIC are added to the Proposition 65 list.


Diaminotoluene (mixed) was added to the Proposition 65 list of chemicals known to the state to cause cancer on January 1, 1990, under the authoritative bodies provision of Proposition 65.2 It was formally identified by the US Environmental Protection Agency (US EPA) as causing cancer (US EPA, 19883).


OEHHA received a petition from Big Lots Stores, Inc. (petition can be found here) for reconsideration of listing for diaminotoluene (mixed) on October 21, 2014. While the US EPA (1988) basis document indicates that the hazard ranking of diaminotoluene (mixed) “is applicable to all isomers of diaminotoluene”, and that the “evidence on potential carcinogenicity from animal studies is “sufficient””, the US EPA document also indicates that “this evidence is based on the carcinogenic properties of the isomer 2,4-diaminotoluene”. No other information on the mixture or individual isomers is included in the US EPA document.



For more information on Diaminotoluene (mixed) please visit the OEHHA website above. Please contact Nexreg for Prop 65 Compliance.

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