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ECHA’s Second Report to EC on Alternative Test Methods Shows Rise in Use of Methods

This news update on Alternative Test Methods is brought to you by SpecialChem.



ECHA’s second report to the European Commission on the use of alternative test methods under REACH shows an increase in the use of these methods. The report’s analysis is based on over 38 000 registration dossiers submitted for the 2010 and 2013 registration deadlines.


According to the report, most registrants do conform with the data sharing obligation under REACH to fulfil the information requirements and to avoid unnecessary animal testing. Registrants also built categories and predicted substance properties using read-across approaches in up to 75 % of analyzed dossiers for at least one endpoint. Read-across or category approach has been particularly used for higher-tier endpoints where alternative, non-animal test methods are not yet available.


In addition, registrants started to take up in vitro methods for skin and eye irritation, using cells, tissues or organs. The total number of in vitro studies submitted for skin and eye irritation has tripled since 2011: almost 20% of analyzed dossiers contained them for these endpoints.



For more information on Alternative Test Methods, please visit the SpecialChem link above. Please contact Nexreg for our REACH compliance services.

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