From the EPA’s High Production Volume (HPV) Challenge Program:

The US, Canada, and Mexico will work together to ensure the safe manufacture and use of industrial chemicals. The partnership will be built on EPA’s ongoing efforts to study and characterize the risks of chemicals that are produced in high volumes. The US is committing to complete, by 2012, risk characterizations and initiate needed actions on more than 9,000 chemicals produced above 25,000 pounds per year in the country.

The EPA provides a number of links, including:

Thank you to reader Mark G. for the link.